Suppressive effects of the Chinese herbal remedy Tripterygium wilfordii Hook f on eosinophilia and IgE hyperproduction in mice
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Suppressive effects of the Chinese herbal remedy Tripterygium wilfordii Hook f on eosinophilia and IgE hyperproduction in mice
The effects of chloroform extract of Tripterygium wilfordii Hook f (TWH extract) on eosinophilia and IgE hyperproduction induced by Mesocestoides cortii infection were examined in BALB/c mice. Mice were infected with M. cortii by intraperitoneal injection of 500 tetrathyridia. The number of peripheral blood eosinophils and IgE levels were examined 21 days after infection. Oral administration of...
متن کاملEffects of the extract of a Chinese herb Tripterygium wilfordii hook f on rat pituitary gland.
In China, the ethylacetate extract of the herb Tripterygium wilfordii Hook f (TWEE), containing the major active ingredient triptolide, is often used with favorable effect on rheumatoid arthritis patients, in alternation with the use of prednisone. The mechanism of this therapeutic effect, however, has not been completely delineated. In this study, we studied how TWEE and prednisone affect the ...
متن کاملHematotoxicity of the chinese herbal medicine Tripterygium wilfordii hook f in CD34-positive human bone marrow cells.
T2, a chloroform/methanol extract of the herb Tripterygium wilfordii Hook f, has been used in China for the treatment of autoimmune and inflammatory diseases for many years. Recent experimental evidence has confirmed that T2 has potent anti-inflammatory and immunosuppressive activity, and a United States Food and Drug Administration-approved clinical trial is currently exploring the efficacy of...
متن کاملNeurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb Tripterygium wilfordii Hook F, on dopaminergic neurons.
It has been reported recently that the immunosuppressant FK506 produced neurotrophic and neuroprotective effects on dopaminergic neurons in vitro and in vivo. We investigated whether tripchlorolide, an immunosuppressive extract of Chinese herb Tripterygium wilfordii Hook F, could exert similar neurotrophic and neuroprotective effects similar to those of FK506. It was found that tripchlorolide p...
متن کاملTherapeutic impact of the ethyl acetate extract of Tripterygium wilfordii Hook F on nephritis in NZB/W F1 mice
This study was designed to examine the potential use of the ethyl acetate (EA) extract of Tripterygium wilfordii Hook F (TwHF), a Chinese herbal medicine, in the treatment of systemic lupus erythematosus. A total of 48 28-week-old female NZB/W F1 mice were randomly divided into three groups and orally administered vehicle or the EA extract of TwHF at 18.25 mg/kg (EAlow) or 36.5 mg/kg (EAhigh) f...
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ژورنال
عنوان ژورنال: Allergology International
سال: 2000
ISSN: 1323-8930
DOI: 10.1046/j.1440-1592.2000.00156.x